• Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation 

      Mikus, Maria Sparreman; Kolmert, Johan; Andersson, Lars I.; Östling, Jörgen; Knowles, Richard G.; Gómez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Khoonsari, Payam Emami; Dahlén, Barbro; Kupczyk, Maciej; de Meulder, Bertrand; Auffray, Charles; Bakke, Per S.; Beghe, Bianca; Bel, Elisabeth H.; Caruso, Massimo; Chanez, Pascal; Chawes, Bo; Fowler, Stephen J.; Gaga, Mina; Geiser, Thomas; Gjomarkaj, Mark; Horváth, Ildikó; Howarth, Peter H.; Johnston, Sebastian L.; Joos, Guy; Krug, Norbert; Montuschi, Paolo; Musial, Jacek; Niżankowska-Mogilnicka, Ewa; Olsson, Henric K.; Papi, Alberto; Rabe, Klaus F.; Sandström, Thomas; Shaw, Dominick E.; Siafakas, Nikolaos M.; Uhlén, Mathias; Riley, John H.; Bates, Stewart; Middelveld, Roelinde J.M.; Wheelock, Craig E.; Chung, Kian Fan; Adcock, Ian M.; Sterk, Peter J.; Djukanovic, Ratko; Nilsson, Peter; Dahlén, Sven-Erik; James, Anna (Journal article; Peer reviewed, 2022)
      Rationale Asthma phenotyping requires novel biomarker discovery. Objectives To identify plasma biomarkers associated with asthma phenotypes by application of a new proteomic panel to samples from two well-characterised ...
    • The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts 

      Hou, Ruihua; Ye, Gang; Cheng, Xiaojing; Shaw, Dominick E.; Bakke, Per S.; Caruso, Massimo; Dahlen, Barbro; Dahlen, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Auffray, Charles; De Meulder, Bertrand; Sousa, Ana R.; Adcock, Ian M.; Fan Chung, Kian; Sterk, Peter J.; Skipp, Paul J.; Schofield, James; Djukanović, Ratko (Journal article; Peer reviewed, 2023)
      Background: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate the ...